Pyroptosis, a lytic form of programmed cell death mediated by gasdermin family pore-forming proteins, has rapidly emerged as a pivotal research theme in cell death and immunology in recent years. Gasdermin proteins are highly conserved across a wide range of species—from mammals and fungi to bacteria—and play essential and diverse roles in host defense and the maintenance of immune homeostasis.
For the first time, we are convening a Keystone-style symposium dedicated to this remarkable protein family. The organizers are Vishva DIXIT (Genentech), Veit HORNUNG (Ludwig Maximilian University of Munich), Feng SHAO (National Institute of Biological Sciences, Beijing) and Hao WU (Harvard Medical School). The meeting will comprehensively explore both inflammasome-dependent and inflammasome-independent functions of gasdermins across model organisms and human systems. Sessions will also address the mechanistic and structural basis of gasdermin autoinhibition, activation, and post-translational regulation, as well as their promising applications in the development of novel therapeutics for a range of human diseases.
We cordially invite you to attend the SMART Symposium: Pyroptosis and Gasdermin Biology to be held at the Cloud Park International Conference Center, Shenzhen, China from September 9 to 11, 2026.
This conference will feature Short Talk and poster presentation session. We sincerely invite you to participate in the Short Talk or poster presentation (encouraging the display of the latest research advancements or unpublished research topics).
Please scan the QR code or click the link https://symposia.smart.org.cn/sym/event/FutureEvents/20250908001.html to register.